Pluvicto® Therapy for Advanced Prostate Cancer

Virginia Urology is proud to offer Pluvicto, an advanced, targeted therapy for certain types of metastatic prostate cancer.

This innovative treatment delivers radiation directly to cancer cells, helping slow disease progression while minimizing damage to healthy tissue.

What is Pluvicto?

Pluvicto® is an FDA-approved treatment for men with advanced prostate cancer that has spread beyond the prostate and is no longer responding to standard hormone therapy. 

It is specifically used for:

• PSMA-positive metastatic castration-resistant prostate cancer (mCRPC)
• Patients who have already received hormone therapy and other treatments

This therapy represents a major advancement in precision cancer care.

Who is a Candidate for Pluvicto®?

You may be a candidate if:

• Your prostate cancer has spread (metastatic)
• Your cancer is no longer responding to hormone therapy
• Imaging confirms PSMA-positive disease
• You have already received other prostate cancer treatments

Our specialists will perform advanced imaging and evaluation to determine if this therapy is right for you. 

How Pluvicto Works (Radioligand Therapy Explained)

Pluvicto is part of a new class of treatments called radioligand therapy. 

Here’s how it works: 

• The drug travels through your bloodstream
• It targets prostate cancer cells using a protein called PSMA
• Once attached, it delivers a small amount of radiation directly to the cancer cells
• This damages the cancer cells and limits their ability to grow and spread

Think of it as precision-guided radiation from inside the body. 

Benefits of Pluvicto Treatment

Clinical studies have shown that Pluvicto can:

• Significantly delay cancer progression
• Reduce the risk of disease worsening or death
• Improve progression-free survival
• Provide a targeted option when other treatments are no longer effective

For many patients, this means:

• More time
• Better disease control
• Improved quality of life

What to Expect During Treatment

• Pluvicto is given through an IV (intravenous infusion)
• Treatment is typically administered in cycles over several months
• Each visit is outpatient
• You will be monitored closely by your care team

Because this therapy involves a radioactive component, you may receive temporary safety instructions after treatment. 

Safety & Side Effects

Pluvicto is generally well tolerated, but like all cancer therapies, it can have side effects. 

Common or possible side effects include: 

• Fatigue
• Dry mouth
• Nausea
• Low blood cell counts 
• Kidney function changes

Because the treatment involves radiation:

• You may need to limit close contact with others for a short period after treatment
• Your care team will provide clear safety instructions to follow at home

Why Choose Virginia Urology for Pluvicto?

Frequently Asked Questions

Want to learn more?

If you or a loved one has advanced prostate cancer, you may have more options than you realize. Schedule a consultation with Virginia Urology to learn if Pluvicto is right for you.

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